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1.

Making glaucoma genetic studies more diverse.

Mackey, David A; Staffieri, Sandra E.

Cell; 187(2): 273-275, 2024 01 18.

Artículo en Inglés | MEDLINE | ID: mdl-38242084

2.

Repeat polymorphisms underlie top genetic risk loci for glaucoma and colorectal cancer.

Mukamel, Ronen E; Handsaker, Robert E; Sherman, Maxwell A; Barton, Alison R; Hujoel, Margaux L A; McCarroll, Steven A; Loh, Po-Ru.

Cell; 186(17): 3659-3673.e23, 2023 08 17.

Artículo en Inglés | MEDLINE | ID: mdl-37527660

3.

Preservation of vision after CaMKII-mediated protection of retinal ganglion cells.

Guo, Xinzheng; Zhou, Jing; Starr, Christopher; Mohns, Ethan J; Li, Yidong; Chen, Earnest P; Yoon, Yonejung; Kellner, Christopher P; Tanaka, Kohichi; Wang, Hongbing; Liu, Wei; Pasquale, Louis R; Demb, Jonathan B; Crair, Michael C; Chen, Bo.

Cell; 184(16): 4299-4314.e12, 2021 08 05.

Artículo en Inglés | MEDLINE | ID: mdl-34297923

4.

Apolipoprotein E4 impairs the response of neurodegenerative retinal microglia and prevents neuronal loss in glaucoma.

Margeta, Milica A; Yin, Zhuoran; Madore, Charlotte; Pitts, Kristen M; Letcher, Sophia M; Tang, Jing; Jiang, Shuhong; Gauthier, Christian D; Silveira, Sebastian R; Schroeder, Caitlin M; Lad, Eleonora M; Proia, Alan D; Tanzi, Rudolph E; Holtzman, David M; Krasemann, Susanne; Chen, Dong Feng; Butovsky, Oleg.

Immunity; 55(9): 1627-1644.e7, 2022 09 13.

Artículo en Inglés | MEDLINE | ID: mdl-35977543

5.

A molecular switch for neuroprotective astrocyte reactivity.

Cameron, Evan G; Nahmou, Michael; Toth, Anna B; Heo, Lyong; Tanasa, Bogdan; Dalal, Roopa; Yan, Wenjun; Nallagatla, Pratima; Xia, Xin; Hay, Sarah; Knasel, Cara; Stiles, Travis L; Douglas, Christopher; Atkins, Melissa; Sun, Catalina; Ashouri, Masoumeh; Bian, Minjuan; Chang, Kun-Che; Russano, Kristina; Shah, Sahil; Woodworth, Mollie B; Galvao, Joana; Nair, Ramesh V; Kapiloff, Michael S; Goldberg, Jeffrey L.

Nature; 626(7999): 574-582, 2024 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-38086421

6.

Reprogramming to recover youthful epigenetic information and restore vision.

Lu, Yuancheng; Brommer, Benedikt; Tian, Xiao; Krishnan, Anitha; Meer, Margarita; Wang, Chen; Vera, Daniel L; Zeng, Qiurui; Yu, Doudou; Bonkowski, Michael S; Yang, Jae-Hyun; Zhou, Songlin; Hoffmann, Emma M; Karg, Margarete M; Schultz, Michael B; Kane, Alice E; Davidsohn, Noah; Korobkina, Ekaterina; Chwalek, Karolina; Rajman, Luis A; Church, George M; Hochedlinger, Konrad; Gladyshev, Vadim N; Horvath, Steve; Levine, Morgan E; Gregory-Ksander, Meredith S; Ksander, Bruce R; He, Zhigang; Sinclair, David A.

Nature; 588(7836): 124-129, 2020 12.

Artículo en Inglés | MEDLINE | ID: mdl-33268865

7.

Transcriptomic analysis of the ocular posterior segment completes a cell atlas of the human eye.

Monavarfeshani, Aboozar; Yan, Wenjun; Pappas, Christian; Odenigbo, Kenechukwu A; He, Zhigang; Segrè, Ayellet V; van Zyl, Tavé; Hageman, Gregory S; Sanes, Joshua R.

Proc Natl Acad Sci U S A; 120(34): e2306153120, 2023 08 22.

Artículo en Inglés | MEDLINE | ID: mdl-37566633

8.

Rare protective variants and glaucoma-relevant cell stressors modulate Angiopoietin-like 7 expression.

Aboobakar, Inas F; Collantes, Edward Ryan A; Hauser, Michael A; Stamer, W Daniel; Wiggs, Janey L.

Hum Mol Genet; 32(15): 2523-2531, 2023 07 20.

Artículo en Inglés | MEDLINE | ID: mdl-37220876

9.

Early Proteomic Characteristics and Changes in the Optic Nerve Head, Optic Nerve, and Retina in a Rat Model of Ocular Hypertension.

Lin, Danting; Wu, Shen; Cheng, Ying; Yan, Xuejing; Liu, Qian; Ren, Tianmin; Zhang, Jingxue; Wang, Ningli.

Mol Cell Proteomics; 22(11): 100654, 2023 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-37793503

10.

Longitudinal in vivo Ca²⁺ imaging reveals dynamic activity changes of diseased retinal ganglion cells at the single-cell level.

Li, Liang; Feng, Xue; Fang, Fang; Miller, David A; Zhang, Shaobo; Zhuang, Pei; Huang, Haoliang; Liu, Pingting; Liu, Junting; Sredar, Nripun; Liu, Liang; Sun, Yang; Duan, Xin; Goldberg, Jeffrey L; Zhang, Hao F; Hu, Yang.

Proc Natl Acad Sci U S A; 119(48): e2206829119, 2022 11 29.

Artículo en Inglés | MEDLINE | ID: mdl-36409915

11.

Pericyte dysfunction and loss of interpericyte tunneling nanotubes promote neurovascular deficits in glaucoma.

Alarcon-Martinez, Luis; Shiga, Yukihiro; Villafranca-Baughman, Deborah; Belforte, Nicolas; Quintero, Heberto; Dotigny, Florence; Cueva Vargas, Jorge L; Di Polo, Adriana.

Proc Natl Acad Sci U S A; 119(7)2022 02 15.

Artículo en Inglés | MEDLINE | ID: mdl-35135877

12.

Viral infections and pathogenesis of glaucoma: a comprehensive review.

Ahmad, Faraz; Deshmukh, Nikhil; Webel, Aaron; Johnson, Sandra; Suleiman, Ayman; Mohan, Rajiv R; Fraunfelder, Frederick; Singh, Pawan Kumar.

Clin Microbiol Rev; 36(4): e0005723, 2023 Dec 20.

Artículo en Inglés | MEDLINE | ID: mdl-37966199

13.

Targeting YAP/TAZ mechanosignaling to ameliorate stiffness-induced Schlemm's canal cell pathobiology.

Li, Haiyan; Kuhn, Megan; Kelly, Ruth A; Singh, Ayushi; Palanivel, Kavipriya Kovai; Salama, Izzy; De Ieso, Michael L; Stamer, W Daniel; Ganapathy, Preethi S; Herberg, Samuel.

Am J Physiol Cell Physiol; 326(2): C513-C528, 2024 Feb 01.

Artículo en Inglés | MEDLINE | ID: mdl-38105758

14.

Intracellular Zn²⁺ promotes extracellular matrix remodeling in dexamethasone-treated trabecular meshwork.

Liu, Canying; Tang, Jiahui; Chen, Yuze; Zhang, Qi; Lin, Jicheng; Wu, Siting; Han, Jiaxu; Liu, Zhe; Wu, Caiqing; Zhuo, Yehong; Li, Yiqing.

Am J Physiol Cell Physiol; 326(5): C1293-C1307, 2024 May 01.

Artículo en Inglés | MEDLINE | ID: mdl-38525543

15.

Novel mutation in EFEMP1 identified from two Chinese POAG families differentially activated endoplasmic reticulum stress markers and induced glaucoma in mouse.

Xiao, Xiaoqiang; Chen, Chong-Bo; Wu, Zhenggen; Ye, Yuhang; Deng, Fang; Cao, Yingjie; Liu, Pingting; Zhang, Mingzhi.

J Cell Biochem; 125(1): 45-58, 2024 01.

Artículo en Inglés | MEDLINE | ID: mdl-38083999

16.

Automated AI labeling of optic nerve head enables insights into cross-ancestry glaucoma risk and genetic discovery in >280,000 images from UKB and CLSA.

Han, Xikun; Steven, Kaiah; Qassim, Ayub; Marshall, Henry N; Bean, Cameron; Tremeer, Michael; An, Jiyuan; Siggs, Owen M; Gharahkhani, Puya; Craig, Jamie E; Hewitt, Alex W; Trzaskowski, Maciej; MacGregor, Stuart.

Am J Hum Genet; 108(7): 1204-1216, 2021 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-34077762

17.

Glaucoma: now and beyond.

Jayaram, Hari; Kolko, Miriam; Friedman, David S; Gazzard, Gus.

Lancet; 402(10414): 1788-1801, 2023 11 11.

Artículo en Inglés | MEDLINE | ID: mdl-37742700

18.

Role of APOE in glaucoma.

Yi, Wenhua; Lv, De; Sun, Yue; Mu, Jingyu; Lu, Xuejing.

Biochem Biophys Res Commun; 694: 149414, 2024 Jan 29.

Artículo en Inglés | MEDLINE | ID: mdl-38145596

19.

The anti-apoptotic role of Ginkgolide B via mitochondrial permeability transition pore inhibition in retinal ischemia-reperfusion.

Wang, Xiou; Hu, Baoqi; Zhang, Hanyue; Zhou, Sijia; Wu, Wenfei; Tan, Zizhu; Sun, Meiqi; Kang, Qianyan.

Biochem Biophys Res Commun; 705: 149722, 2024 Apr 23.

Artículo en Inglés | MEDLINE | ID: mdl-38442447

20.

Th1 cells contribute to retinal ganglion cell loss in glaucoma in a VCAM-1-dependent manner.

He, Chong; Peng, Kun; Zhu, Xiong; Wang, Zuo; Xiu, Wenbo; Zhang, Gao; Chen, Yang; Sun, Chaonan; Xiao, Xiao; Liu, Donghua; Li, An; Gao, Yanping; Wang, Jinxia; Shuai, Ping; Chen, Yilian; Yu, Ling; Lu, Fang.

J Neuroinflammation; 21(1): 43, 2024 Feb 05.

Artículo en Inglés | MEDLINE | ID: mdl-38317227

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